|Դu(y)¡?wn)|¹̥
59 2023-03-18
ϺF{(ln)(f)ǰׇfƬôӣϺF{(ln)(f)ǰׇfƬôʹãt(y)ˎW(wng)ѼP(gun)ϺF{(ln)(f)ǰׇfƬf(shu)(sh),ϺF{(ln)(f)ǰׇfƬr(ji),ϺF{(ln)(f)ǰׇfƬX,ϺF{(ln)(f)ǰׇfƬĹЧc,ϺF{(ln)(f)ǰׇfƬ÷cˎƷϢȫԃʹã
ƷQ:ϺF{(ln)(f)ǰׇfƬ
(zhn)̖(ho):(gu)ˎ(zhn)0120H2432
:Ʒ(li)SRҊ(jin)ԭ(du)ƷʬF(xin)ˎί(x)Ⱦ腢ˎY(ji)ƷҪm(yng)YоµиȾ1.cϣUײ١cU殐׃ΗUͨ׃ΗUĪоµ·Ⱦ2.ѪU2qСж3.ѪUµij֧l(f)4.ɸϻ־RоµcȾ־RȾ5.ίϷx(chng)Ʒϵx6.Ϸx(chng)A(y)пϷx(chng)һΰl(f)ʷĻߣHIV˸ȾCD4ܰͼ(x)Ӌ(j)(sh)200/mm3ڿܰͼ(x)(sh)20%7.ɮa(chn)cشcϣU(ETEC)߸a
÷:1.˳ί(x)ԸȾһμS160mgͻǰׇf800mgÿ12Сr(sh)1ίϷx(chng)һμS3.755mg/kgǰׇf18.7525mg/kgÿ6Сr(sh)1A(y)ˎS160mgͻǰׇf800mgһ2^ͬһշ1һܷ32.С2냺ί(x)Ⱦ2(g)w40kgµċ׃wؿڷһSMZ2030mg/kgTMP46mg/kgÿ12Сr(sh)1wء40kgСͬ˳ίx(chng)Ⱦ翨Ϸx(chng)wһοڷSMZ18.7525mg/kgTMP3.755mg/kgÿ6Сr(sh)1֧l(f)į1014գ·Ⱦį710(x)į̞57գͯжį̞10Ϸx(chng)į̞1421
ͨQ
(f)ǰׇfƬ
Σ
?Ʒ(li)SRҊ(jin)ԭ(du)ƷʬF(xin)ˎί(x)Ⱦ腢ˎY(ji)ƷҪm(yng)YоµиȾ
1.cϣUײcU١殐׃ΗUͨ׃ΗUĪоµ·Ⱦ
2.ѪU2qСж
3.ѪUµij֧l(f)
4.ɸϻ־RоµcȾ־RȾ
5.ίϷx(chng)Ʒϵx
6.Ϸx(chng)A(y)пϷx(chng)һΰl(f)ʷĻHIV˸ȾCD4ܰͼ(x)Ӌ(j)(sh)200/mm3ڿܰͼ(x)(sh)20%
7.ɮa(chn)cشcϣU(ETEC)߸a
÷
1.˳ί(x)ԸȾһμS160mgͻǰׇf800mgÿ12Сr(sh)1ίϷx(chng)һμS3.755mg/kgǰׇf18.7525mg/kgÿ6Сr(sh)1A(y)ˎS160mgͻǰׇf800mgһ2^ͬһշ1Σһܷ3
2.С2냺ί(x)Ⱦ2(g)w40kgµċ׃wؿڷһSMZ2030mg/kgTMP46mg/kgÿ12Сr(sh)1wء40kgСͬ˳
ίx(chng)Ⱦ翨Ϸx(chng)wһοڷSMZ18.7525mg/kgTMP3.755mg/kgÿ6Сr(sh)1
֧l(f)į1014·Ⱦį710գ(x)į̞57ͯжį̞10Ϸx(chng)į̞1421
(yng)
1.^(gu)(yng)^鳣Ҋ(jin)ɱF(xin)ˎ(yn)߿ɰl(f)BԶμtÓƤʹƤɽήsƤҲбF(xin)(yng)ˎP(gun)(ji)ʹl(f)Ѫ岡ӷ(yng)żҊ(jin)^(gu)ݿ
2.(x)pٻȱYѪСpٰYϵKؚѪ߿ɱF(xin)ʹl(f)nͳѪA
3.ѪؚѪѪt@ȱ-6-ÓøĻߑ(yng)ûǰˎڰl(f)С^˞Ҋ(jin)
4.đtѪYS㡣ڱƷcđtظ(jng)(zhng)Y(ji)ϲλxđtιܲ(du)đt̎^װl(f)đtѪYSżɰl(f)S
5.Kpɰl(f)Sιܜp(yn)߿ɰl(f)ԸΉ
6.IKpɰl(f)Y(ji)Ѫżл߰l(f)g|(zh)IIС܉ć(yn)ز(yng)
7.ġIθ{pˡa^ʹȣһYpżл߰l(f)Dyc˕r(sh)ͣˎ
8.נ[ܜpżаl(f)
9.И(jng)ϵy(tng)Է(yng)żɰl(f)F(xin)龫e(cu)yϵKX(ju)л
10.żɰl(f)o(w)XĤ^ʹi(xing)(qing)ֱĵȱF(xin)
Ʒµć(yn)ز(yng)mҊ(jin)ۼٲBԶμtÓƤƤɽήsƤסl(f)ԸΉ(x)ȱYϵKؚѪѪҺϵy(tng)̲ߵ(yng)^ǰ̲ߞҊ(jin)
ɣ
1.(du)SMZTMP^(gu)߽
2.ڱƷֹ~Ĵxؾt(x)ؚѪ~}ȱԓ߽ñƷ
3.ЋDڋDŮñƷ
4.С2(g)µċ냺ñƷ
5.ضȸIܓp߽ñƷ
ע(xing)
l.(x)мxñƷίA(y)ˎ
(1)жA(y)L(zhng)ί
(2)AMѪw
2.^(gu)(yng)(du)һNǰˎʬF(xin)^(gu)Ļߌ(du)ǰˎҲ^(gu)
3.Kpɰl(f)S㡢ιܜp(yn)߿ɰl(f)ԸΉиιܓp˱⑪(yng)
4.IKpɰl(f)Y(ji)ѪʷñƷg(yng)ˮָ瑪(yng)ñƷL(zhng)r(sh)ˮ⣬̼ͬcԷֹ˲(yng)ʧˮݿ˺껼ߑ(yng)ñƷIp(yng)û⑪(yng)ñƷIܜp˻߲ˑ(yng)ñƷ
5.(du)ˎ̼øˎʬF(xin)^(gu)Ļ(du)ǰˎ^(gu)
6.r(yng)ãȱ-6-ÓøѪ߲Y~ȱѪҺϵy(tng)ʧˮ̲ݿ˺껼
7.ˎgעz
(1)ȫѪz(du)L(zhng)ÄI(yng)B(yng)ÿdBˎĻȞҪ
(2)ίБ(yng)Һz(ÿ23ղҎ(gu)һ)l(f)F(xin)L(zhng)̻߄ίr(sh)ܰl(f)ĽY(ji)
(3)Iܙz
8.(yn)ظȾߑ(yng)y(c)Ѫˎ(du)(sh)Ⱦxǰ_(d)50150mg/ml((yn)ظȾ120150mg/ml)ЧǰѪȲ(yng)^(gu)200mg/ml糬^(gu)˝(yng)l(f)
9.ӴˎΔ(sh)L(zhng)̣Էeж
10.ڱƷƴcUL(zhng)KBSc(ni)ĺϳʹñƷ^(gu)һ(yng)ͬr(sh)oSBA(y)ȱ
11.ñƷ~ȱr(sh)ͬr(sh)~Ƅ߲ɔ_TMPĿ(x)Ѻϳɵ~йl(f)(yng)ͣñƷo~36mgעһ1Σʹ2ջ(j)ҪˎѪܻ֏(f)(du)L(zhng)^(gu)ʹñƷ߿ɽo߄~ᲢL(zhng)̡
ɷݣ
Ʒ(f)ƄÿƬԳɷֻǰׇf0.4gͼS0.08g
Ԡ
ƷɫƬ
ЋDڋDŮˎ
1.Ʒɴ^(gu)Ѫ̥P̥w(ni)(dng)(sh)(yn)l(f)F(xin)»оȱYЋD˱⑪(yng)
2.Ʒ֭з֭Нȼs_(d)ĸwѪˎȵ50%100%ˎ܌(du)냺a(chn)ӰƷ-6-ÓøȱБ(yng)Ќ(do)ѪؚѪl(f)ĿܡbԭڋDŮˑ(yng)ñƷ
ͯˎ
ڱƷcđtظ(jng)(zhng)Ѫ{ϵĽY(ji)ϲλD(zhun)øϵy(tng)δl(f)ƣǰxѪ˺Sl(f)ΣU(xin)ԓˎ2(g)냺đ(yng)Ìٽͯ̎L(zhng)l(f)I߀ˎ(yng)Üp
ˎ
껼ߑ(yng)ñƷr(sh)l(f)(yn)ز(yng)ęC(j)(hu)ӣ(yn)ƤƤw^(gu)(yng)(x)pٺѪСpٵѪҺϵy(tng)ͬr(sh)(yng)ˎ߸װl(f)껼˱ʹ_ָr(sh)(qun)Q
ˎã
1.AˎӱƷډAеܽʹй
2.c(du)ã(du)ɴ汾Ʒ(x)zȡ
3.ˎcƷͬÕr(sh)Ʒȡ@ЩˎĵY(ji)ϲλxˎÕr(sh)gL(zhng)l(f)Է(yng)ˮ(dng)@ЩˎcƷͬr(sh)(yng)ãڑ(yng)ñƷ֮ʹÕr(sh){(dio)䄩ˎڷˎڷѪˎװӢcc
4.cˎÿ(qing)ˎ(du)Ѫϵy(tng)IJ(yng)(x)ѪСpٵ_ָˎͬÕr(sh)(yng)(yn)^ܰl(f)ĶԷ(yng)
5.cˎ(Ƽ)L(zhng)r(sh)gÿɌ(do)±еĿɿԜp٣ӽ(jng)ѪęC(j)(hu)
6.c˨ˎÕr(sh)䝓ڵĶ
7.cζˎÕr(sh)ζl(f)ʵ(du)ˎr(sh)g^L(zhng)иβʷߑ(yng)O(jin)y(c)ι
8.cˎÕr(sh)ܰl(f)õӡ
9.ܱƷίߌ(du)SKҪ
10.cƷã?yn)Ʒпɷֽa(chn)ȩ߿cƷγɲԳʹl(f)Y(ji)ΣU(xin)
11.Ʒȡ̩ɵѪ{Y(ji)ϲλ(dng)ͬÕr(sh)(qing)̩ɵ
12.ͪcƷÕr(sh)ɜpٺIСܵķѪˎȳ־a(chn)Է(yng)ڑ(yng)ûͪgڑ(yng)ίҪ{(dio)ƷĄ(dng)ͪ^L(zhng)r(sh)(du)ƷѪˎM(jn)бO(jin)y(c)ڄ{(dio)Cȫˎ
13.ƷеTMPAֵĴx(qing)俹á
14.ƷеTMPch(hun)غÿI
15.ƽcƷÕr(sh)@ʹƷеTMPӺѪ˥ڿs
16.c[ˎ24-ˎҲڑ(yng)~ˎίį֮g(yng)ñƷ?yn)Юa(chn)t(x)ؚѪĿ
17.ccƷеTMPÃѪˎȾߣȵʹ(yng)ҼǸFѪtѪYİl(f)
18.cùˎ?yn)鱾Ʒпܸɔ_ˎĚ
ˎã
ԓƷǰˎǻǰאSMZcSणTMPď(f)ƄԓƷÙC(j)ƞ飺SMZڶ~ϳøɔ_ϳ~ĵһTMP~ϳɴxĵڶxƶ~߀ԭøߺÿʹ(x)~xܵpࡣԓƷąf(xi)ͬ^ˎ(qing)(du)ʬF(xin)ˎpȻ(li)(x)(du)ԓƷˎڅ(sh)
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